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Thyroid Ablation

Thyroid Nodules/Cyst

Thyroid nodules are common and occur in up to 50% of the adult population. Although most thyroid nodules are benign, some nodules require treatment for cosmetic reasons, subjective symptoms or anxiety about a malignant change. Furthermore, if large compressive thyroid nodules are untreated, they may result in life-threatening conditions because of the potential acute onset of respiratory crisis.

The conventional treatments for thyroid nodules are levothyroxine medication and thyroid surgery. However, both surgery and medication have drawbacks. Although surgery is good option, it can cause some problems such as upper airway obstruction, non-esthetic scars, injuries to the laryngeal nerves, iatrogenic hypothyroidism and so on. Moreover, the efficacy of thyroid hormone suppressive therapy is still controversial.

Microwave ablation is a safe and effective technique for the treatment of benign thyroid nodules. It ablation can achieve shrinkage of nodule size and relief of clinical symptoms. Side effects and failures are few.


Para Thyroid Adenoma

Primary hyperparathyroidism is the third most common endocrine disorder, with its highest incidence being in postmenopausal women. In hyperparathyroidism, in the absence of a known or recognized stimulus, one or more of the four parathyroid glands secrete excess parathyroid hormone (PTH), resulting in hypercalcemia. Single-gland adenoma is the most common, cause (75%–85%), multigland adenoma arises in a substantial proportion (two glands in 2%–12% of cases)

The standard therapy for hyperparathyroidism is surgical removal of a parathyroid adenoma or adenomas. Newer treatment modality like Microwave ablation is a safe and effective technique for the treatment of hyperparathyroidism with parathyroid nodules. It can reduce adenoma size, decrease serum PTH and calcium levels, and relieve nodule-related symptoms with minimal hospital stay and morbidity.


Thyroid Cancer

Thyroid cancer is the most common endocrine malignancy. Papillary thyroid carcinoma (PTC) is the most common subtype of the thyroid cancer and it has a clinically silent course and a relatively low mortality rate. Although it frequently spreads locally and recurs by metastasising to local cervical lymph nodes. The overall recurrence and mortality rates for well-differentiated thyroid cancers (papillary and follicular thyroid carcinomas) are 20.5% and 8.4%, respectively, at a mean follow-up of 11.3 years.

If a minimally invasive technique could eradicate these small nodules, then it may become a potential therapeutic approach in these patients. Ultrasound guided percutaneous microwave ablation appears to be safe and effective for inducing complete necrosis of solitary papillary carcinoma( less then 10mm).

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